Muchikamu chebiotechnology uye biopharmaceutical fields, mazwi ekuti "bioreactor" uye "biofermenter" anowanzoshandiswa zvakasiyana, asi anoreva masisitimu akasiyana ane mabasa chaiwo uye mashandisirwo. Kunzwisisa mutsauko uripo pakati pemhando mbiri idzi dzemidziyo yakakosha kune nyanzvi mumunda, kunyanya kana kugadzira uye kugadzira masisitimu anosangana akasimba ekudzora zviyero.

Kutsanangura Mitemo

Bioreactor ishoko rakakura rinovhara chero mudziyo umo biological reaction inoitika. Izvi zvinogona kusanganisira maitiro akasiyana sekuvirisa, sero tsika, uye kuita kwe enzyme. Bioreactors inogona kugadzirirwa aerobic kana anaerobic mamiriro uye inogona kutsigira zvakasiyana-siyana zvipenyu, kusanganisira mabhakitiriya, mbiriso, uye maseru anoyamwisa. Iwo akashongedzerwa neakasiyana tembiricha, pH, oksijeni mwero, uye agitation kudzora kuti agone kukwirisa mamiriro ekukura kweakagadzirwa tupukanana kana maseru.

A biofermenter, kune rumwe rutivi, imhando chaiyo yebioreactor iyo inonyanya kushandiswa mukuvirisa maitiro. Fermentation inzira yemetabolism inoshandisa tupukanana, kazhinji mbiriso kana bhakitiriya, kushandura shuga kuita asidhi, magasi, kana doro.Biofermenters zvakagadzirirwa kugadzira nharaunda inokodzera kukura kweaya ma microorganisms, nekudaro achigadzira zvakasiyana-siyana zvebioproducts senge ethanol, organic acids, uye mishonga yemishonga.

Misiyano Yakakosha

Basa:

Bioreactors inogona kushandiswa kune akasiyana bioprocesses, kusanganisira sero tsika uye enzyme maitiro, nepo kuvirisa kwakanyatso kugadzirirwa maitiro ekuvirisa.

Zvidimbu zveDesign:
Biofermentersanowanzo gadzirwa aine mativi chaiwo kuti aenderane nezvinodiwa zvezvipenyu zvinovirisa. Semuyenzaniso, anogona kusanganisira maficha akadai semabaffles ekuvandudza musanganiswa, chaiwo aeration masisitimu ekuvirisa aerobic, uye tembiricha yekudzora masisitimu kuti arambe akakwana ekukura mamiriro.

Application:
MaBioreactors anosiyana-siyana uye anogona kushandiswa kune akasiyana mashandisirwo mumaindasitiri akasiyana, anosanganisira mishonga, chikafu uye zvinwiwa, uye yezvakatipoteredza biotechnology. Kusiyana neizvi, mafermenters anonyanya kushandiswa mumaindasitiri anogadzira zvinhu zvinovirisa, zvakadai sekugadzira waini, kubika, uye kugadzirwa kwebiofuel.

Chikero:
Ose mabioreactors uye mafermenters anogona kugadzirwa kune akasiyana masikero, kubva kutsvagurudzo yemurabhoritari kusvika pakugadzirwa kwemaindasitiri. Zvakadaro, mavirisi anowanzo kuve nehukuru hwakakura hwekugonesa huwandu hukuru hwechigadzirwa chinowanzo gadzirwa panguva yekuvirisa.

Basa reGMP uye ASME-BPE mukugadzira fermenter

Kutevedzera mitemo yemitemo kwakakosha kana zvasvika pakugadzira nekugadzirabio-fermenters. PaVEN, isu tinoona kuti mafermenters edu akagadzirwa uye anogadzirwa mukunyatso kutevedzera Yakanaka Manufacturing Practice (GMP) mirau uye ASME-BPE (American Society of Mechanical Engineers - Bioprocessing Equipment) zvinodiwa. Kuzvipira uku kumhando nekuchengetedza kwakakosha kune vatengi vedu vebiopharmaceutical vanovimba nemidziyo yedu yekuvirisa tsika yehutachiona.

Yedumatangi ekuvirisainoratidzira nyanzvi, mushandisi-inoshamwaridzika uye modular dhizaini inogona kubatanidzwa zviri nyore mumasisitimu aripo. Isu tinopa zvikepe zvinoteerana neakasiyana-siyana erudzi rwekumanikidza ngarava zviyero, zvinosanganisira ASME-U, GB150 uye PED (Pressure Equipment Directive). Izvi zvakasiyana-siyana zvinovimbisa kuti matangi edu anogona kugarisa huwandu hwakawanda hwekushandisa uye zvinodiwa zvekutonga.

Customization uye Versatility

PaVEN, tinonzwisisa kuti mutengi wega wega biopharmaceutical ane zvakasarudzika zvinodiwa. Ndosaka tichipa huwandu hwakazara hwemavirisa ekurima hutachiona, kubva murabhoritari R&D kuenda kukutyaira uye kugadzira maindasitiri. Maviri edu anogona kugadziridzwa kune chaiwo zvinodiwa, kusanganisira huwandu, kubva pa5 litres kusvika 30 kiloliters. Uku kuchinjika kunoita kuti tisangane nezvido zveakanyanya aerobic mabhakitiriya, akadai seEscherichia coli uye Pichia pastoris, ayo anowanzoshandiswa mukugadzirwa kwebiopharmaceutical.

Muchidimbu, nepo ese ari maviri bioreactors uyebiofermentersvanoita basa rakakosha mumunda webiotechnology, anoshandiswa kune zvinangwa zvakasiyana uye akagadzirwa aine akasiyana mabasa mupfungwa. Kunzwisisa misiyano iyi kwakakosha pakusarudza midziyo yakakodzera yekushandisa chaiyo. KuVEN, takazvipira kupa mafermenters emhando yepamusoro anosangana nezvinodiwa neindasitiri yebiopharmaceutical, kuve nechokwadi chekuti vatengi vedu vanogona kuwana mhedzisiro yakanaka mukurima kwavo hutachiona. Kunyangwe iwe uri mumatanho ekutanga ekutsvagisa kana kuwedzera kugadzirwa kwemaindasitiri, hunyanzvi hwedu uye zvigadziriso zvinogoneka zvinogona kukubatsira iwe neushingi kufamba kuomarara kwebioprocessing.